Neurospecific enolase as a nonspecific neurodegenerative process marker
نویسندگان
چکیده
منابع مشابه
[Serum neuron-specific enolase as a prognostic marker after a cardiac arrest].
BACKGROUND AND OBJECTIVES Cardiac arrest is a state of severe cerebral perfusion deficit. Patients recovering from a cardiopulmonary resuscitation are at great risk of subsequent death or incapacitating neurologic injury, including persistent vegetative state. The early definition of prognosis for these patients has ethical and economic implications. The main purpose of this manuscript was to r...
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متن کامل8-OHdG in cerebrospinal fluid as a marker of oxidative stress in various neurodegenerative diseases.
BACKGROUND The 8-hydroxy-2 deoxyguanosine (8-OHdG) is a product of nucleoside oxidation of DNA and a reliable marker of oxidative stress markers. Increased levels of oxidative stress have been reported in the cerebrospinal fluid (CSF) of patients with various neurodegenerative disorders. OBJECTIVE In search of a biochemical indicator of Parkinson's disease (PD), we analyzed the levels 8-OHdG ...
متن کاملPeptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases.
The citrullination of enolase by PAD (peptidylarginine deiminase) has emerged as an important post-translational modification in human disorders; however, the physiological function of citrullination remains unknown. In the present study, we report that citrullination diversely regulates the biological functions of ENO1 (α-enolase) and NSE (neuron-specific enolase). We developed three mouse IgG...
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ژورنال
عنوان ژورنال: Bulletin of Siberian Medicine
سال: 2011
ISSN: 1819-3684,1682-0363
DOI: 10.20538/1682-0363-2011-2-15-21